产品编号：4083597

包装规格：2 MG

产品编号：4083596

纯度规格：A cell permeable competitive inhibitor of Pin1 (EC₅₀ = 4.1 μM, K_i = 50 nM).

包装规格：10 MG

产品编号：4083594

纯度规格：A cell-permeable, potent and competitive inhibitor of fructose-2,6-bisphosphatase 3 (PFKFB3; IC₅₀ = 670 nM).

包装规格：25 MG

产品编号：4083593

纯度规格：A cell-permeable inhibitor of PFKFB3 that reversibly docks to its substrate binding domain (IC₅₀ = 207 nM)

包装规格：25 MG

产品编号：4083592

纯度规格：A cell-permeable nematicidal compound that covalently binds to the peroxidatic cysteine of peroxiredoxin II in T. gondii and irreversibly blocks its hyperperoxidation activity (IC₅₀ = 23 μM).

包装规格：25 MG

产品编号：4083589

纯度规格：A cell-permeable, selective &direct blocker of p18-Cdk6 interaction. Inhibits p18INK4C protein activity &favors HSCs self-renewal by ~4.2-fold.

包装规格：25 MG

产品编号：4083588

纯度规格：A cell-permeable compound with cytotoxicity towards quiescent cells in colon cancer 3-D microtissues (~ 6 μM). Reduces mitochondrial oxidative phosphorylation in tumor cells.

包装规格：10 MG

产品编号：4083587

纯度规格：Prevents melanopsin/Opn4 photoactivation in a reversible manner. Inhibits cellular phototransduction mediated by human Opn4 (IC₅₀ = 665 nM; using CHO transfectants).

包装规格：10 MG

产品编号：4083585

包装规格：10 MG

产品编号：4083584

纯度规格：A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.

包装规格：10 MG

产品编号：4083583

纯度规格：A cell-permeable, potent Nrf-2 activator that stimulates HO-1 expression in murine microglial BV-2 cultures. Induces overall Nrf2 cellular accumulation and nuclear translocation.

包装规格：10 MG

产品编号：4083582

纯度规格：A cell-permeable inhibitor of nonsense-mediated mRNA decay (NMD) that enhances the stability of premature termination codon mutated p53 mRNA in N417 and HDQP-1 cells.

包装规格：10 MG

产品编号：4083581

纯度规格：A cell-potent, bioavailable NLRP3 inflammasome activation inhibitor. Effectively blocks caspase-1 &-11 activation, IL-1β processing and IL-1β &IL-6 secretion.

包装规格：10 MG

产品编号：4083578

包装规格：25 MG

产品编号：4083577

纯度规格：A cell-permeable neomycin derived artificial nucleobase conjugate. Inhibits the production of oncogenic miRNAs 372 (IC₅₀ = 2.4 μM) by binding to pre-miRNAs and interrupts processing by Dicer.

包装规格：2 MG

产品编号：4083576

纯度规格：A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC₅₀ = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).

包装规格：10 MG

产品编号：4083575

纯度规格：A cell-permeable, bioavailable, highly potent inhibitor of acyl CoA:monoacylglycerol acyltransferase 2 inhibitor (MGAT2, IC₅₀ = 3.4 nM). Displays good microsomal stability.

包装规格：5 MG

产品编号：4083573

包装规格：10 MG

产品编号：4083571

纯度规格：A synthetic cyclic alkylaminoluciferin with properties superior to D-luciferin. Binds to luciferase with higher affinity.

包装规格：10 MG

产品编号：4083570

纯度规格：A cell-permeable stain for neutral lipids. Does not stain phospholipids.

包装规格：5 MG

产品编号：4083569

包装规格：5 MG

产品编号：4083567

纯度规格：A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.

包装规格：25 MG

产品编号：4083565

纯度规格：A fast acting, reversible, and selective activator of Kir6.2/SUR1 channels (EC₅₀ = 7 μM).

包装规格：10 MG

产品编号：4083563

纯度规格：A cell-permeable, direct, non-covalent inhibitor of Keap1-Nrf2 protein-protein interaction (Kd = 1 μM) that causes the dissociation of Nrf2 from keap1 in the cytosol.

包装规格：10 MG

产品编号：4083562

包装规格：10 MG

产品编号：4083561

包装规格：5 MG

产品编号：4083560

纯度规格：A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC₅₀ = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).

包装规格：10 MG

产品编号：4083558

纯度规格：A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (~ 5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.

包装规格：25 MG

产品编号：4083557

纯度规格：The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (~25 to 200 nM) upon ER stress induction.

包装规格：10 MG

产品编号：4083556

纯度规格：InSolution^TM Y-27632, Sterile-Filtered, Cell Culture-Tested, CAS 146986-50-7, is a 10 mM sterile-filtered solution of Y-27632 in H₂O. Acts as an inhibitor of Rho kinases (Ki = 140 nM for p160ROCK).

包装规格：2 MG

产品编号：4083555

纯度规格：A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.

包装规格：2 MG

产品编号：4083553

纯度规格：A 25 mM (10 mg/650 μl) sterile-filtered solution of SRT1720, HCl in DMSO.

包装规格：10 MG

产品编号：4083552

纯度规格：A 25 μM (10 mg/583 μL) sterile-filtered solution of Pepstatin A, Synthetic in DMSO.

包装规格：10 MG

产品编号：4083551

包装规格：500 μG

产品编号：4083550

包装规格：5 MG

产品编号：4083549

纯度规格：A 25 mM (1 mg/98 μL) sterile-filtered solution of Histone Methyltransferase EZH2 Inhibitor, DZNep in H₂O.

包装规格：1 MG

产品编号：4083547

纯度规格：A 50 mM (2 mg/106.23 μL) sterile-filtered solution of APT1 Inhibitor, palmostatin B in DMSO.

包装规格：2 MG

产品编号：4083546

纯度规格：A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.

包装规格：1 MG

产品编号：4083545

纯度规格：A cell-permeable, selective inhibitor of E3 ligase complex SCFβTrCP1-mediated ubiquitination of phosphorylated IκBα (IC₅₀ = 5.2 μM).

包装规格：10 MG

产品编号：4083542

纯度规格：A cell-permeable inhibitor of isocitrate dehydrogenase 2 R140Q mutant-containing dimers. Has minimal effect on wild type dimer-catalyzed alpha-KG production.

包装规格：10 MG

产品编号：4083539

纯度规格：A cell-permeable 6-amino-purine based compound that selectively binds to HSP90a (EC₅₀ = 5.4 μM) and inhibits its activity cancer cells.

包装规格：5 MG

产品编号：4083534

纯度规格：A cell-permeable, highly potent, and selective agonist of free fatty acid receptor 1 (FFA1; GPR40; EC₅₀ = 20 nM in FFA1-transfected HEK-293 cells).

包装规格：10 MG

产品编号：4083533

包装规格：10 MG

产品编号：4083532

包装规格：10 MG

产品编号：4083527

包装规格：10 MG

产品编号：4083525

纯度规格：A helical 27-mer peptide with E54Q modification that directly binds to EDD (Kd = 320 nM) and disrupts protein-protein interaction of EED with EZH2 and EZH1.

包装规格：2 MG

产品编号：4083524

纯度规格：A cell-permeable inhibitor of Eya2 ED tyrosine phosphatase (IC₅₀ = 4.1 μM; KD = 2.0 μM for hEya2, catalytic domain)

包装规格：25 MG

产品编号：4083523

纯度规格：A cell-permeable compound that reversibly blocks cellular glycosylation and surface expression of Notch, APP, Klotho by blocking events prior to cargo assembly at the ER exit sites.

包装规格：10 MG

产品编号：4083522

纯度规格：A cell-permeable antagonist of Eph receptors that competitively disrupts Eph2A-ephrin-A1 binding (IC₅₀ = 945 nM; K_i = 345 nM).

包装规格：10 MG

产品编号：4083521

纯度规格：A nitro-benzoxadiazole compound that directly binds to the dimerization domain of sEGF receptor to generate stable dimers and allosterically activate the receptor.

包装规格：25 MG