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BLT-1
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3415618 | 5 MG | 1790 | |||
| 3415618 | 25 MG | 5030 |
产品别名
321673-30-7
BLT-1
33M20
2-Hexyl-1-cyclopentanone thiosemicarbazone
Block lipid transport-1
MIT 9952-53
BLT1
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H23N3S |
| Molecular weight | 241.40 |
| MDL number | MFCD00571007 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825125 |
| NACRES | NA.77 |
| Application【应用】 | BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux. BLT-1 (Block lipid transport-1) has been used as an inhibitor of the SR-BI (scavenger receptor, class B, type I) mediated lipid transfer to determine if miR-223-3p export from polymorphonuclear neutrophils (PMNs) to high-density lipoproteins (HDLs) is dependent on SR-BI-mediated lipid flux. It has also been used as a SR-BI inhibitor to study the effect of HDL on osteocalcin (OCN) expression in monocyte cell lines through SR-B1. |
| Biochem/physiol Actions【生化/生理作用】 | Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥13 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCCCCCC1CCC\C1=N/NC(N)=S |
| InChI | 1S/C12H23N3S/c1-2-3-4-5-7-10-8-6-9-11(10)14-15-12(13)16/h10H,2-9H2,1H3,(H3,13,15,16)/b14-11+ |
| InChI key | OWGUSBISUVLUJF-SDNWHVSQSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
