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小鼠Tnfsf4 /肿瘤坏死因子配体超家族成员4 ELISA试剂盒
Mouse Tnfsf4 / Tumor Necrosis Factor Ligand Superfamily Member 4 ELISA Kit
| 产品编号： | 3155190 |
| 规格： | for serum, plasma and cell culture supernatants |
| 包装规格： | 96 WELLS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
小鼠Tnfsf4 /肿瘤坏死因子配体超家族成员4 ELISA试剂盒
Mouse Tnfsf4 / Tumor Necrosis Factor Ligand Superfamily Member 4 ELISA Kit
产品性质
| species reactivity | mouse |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type serum sample type plasma sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <10% intra-assay cv: <12% sensitivity: 30 pg/mL |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Tnfsf4(22164) |
基本信息
| General description【一般描述】 | This ELISA antibody pair detects mouse TNFSF4/OX40. |
| Application【应用】 | 请参考Protocol了解详情。 |
| Biochem/physiol Actions【生化/生理作用】 | Tumor necrosis factor (TNF) superfamily member 4 (Tnfsf4) signals specifically through the OX40 receptor, which is expressed primarily on CD4+T cells but also on certain activated CD8+T cells. Tnfsf4 acts as a costimulatory signal, which is essential for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3 and interferon γ (IFNg). Tnfsf4 signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene leads to the development of autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc). |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Components【组分】 | 组份可单独销售 RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABSTOP3 ELISA Stop Solution (Item I) RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1) RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1) RABWASH4 20X Wash Buffer (Item B) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
